This collaborative project seeks to explore the impact of solvation effects on molecular and ion recognition within biomolecules and supramolecular systems. Led by a multidisciplinary team of experimental and theoretical researchers specializing in molecular clusters from Japan, the United States, Germany, and France, its aim is to establish a novel academic framework for understanding molecular recognition phenomena.
Crown ethers serve as a prominent illustration of solvation effects, particularly in ion recognition. While these ethers are capable of recognizing ions matching their ring sizes, such recognition is exclusively observed in solution. Hence, solvation effects are indispensable for ion recognition processes. By delving into the role of solvation effects, notably at the local (microscopic) level, this project endeavors to unveil the kinetic mechanisms underlying molecular and ion recognition, distinct from conventional thermodynamic interpretations.
The international research team, comprising experts in gas-phase spectroscopy, synthetic chemists for supra molecular systems and computational chemists, will investigate the influence of microscopic solvation effects on molecular and ion recognition.
Leveraging the complementary strengths of research methodologies, targets, and phenomena among the teams from Japan, the U.S., Germany, and France, this collaboration anticipates synergistic outcomes through joint endeavors. Numerous young researchers and graduate students from each participating laboratory is poised to significantly contribute to fostering globally-oriented young researchers.